Scientific Publications

Francisco Karkow, et al.

AHCC® in Sjögren’s Disease: One Bold Therapeutic Hypothesis

EC Microbiol. 2020; 16(1).

Zaure Zhaparkhanova, et al.

Nutritional Immunotherapy in Autoimmune Thyroid Disease: Preliminary Results

Endocrinology Quick Report. 2018; 2(50): 23-27.

Jean‑François Mallet, et al.

Active Hexose Correlated Compound (AHCC) promotes an intestinal immune response in BALB/c mice and in primary intestinal epithelial cell culture involving toll-like receptors TLR-2 and TLR-4

Eur J Nutr. 2016; 55(1): 139-46.

Loretta Olamigoke, et al.

AHCC Activation and Selection of Human Lymphocytes via Genotypic and Phenotypic Changes to an Adherent Cell Type: A Possible Novel Mechanism of T Cell Activation

Evid Based Complement Alternat Med. 2015; 2015: 508746.

Jun Takanari, et al.

Effects of Active Hexose Correlated Compound on the Seasonal Variations of Immune Competence in Healthy Subjects

J Evid Based Complementary Altern Med. 2015; 20(1): 28-34.

Mari Kogiso, et al.

Active Hexose Correlated Compound and T Cell Response in Hind – Limb – Unloaded BALB/c Mice

Int J Surg. 2015; 2(5): 32-38.

Abdelali Daddaoua, et al.

The nutritional supplement Active Hexose Correlated Compound (AHCC) has direct immunomodulatory actions on intestinal epithelial cells and macrophages involving TLR/MyD88 and NF-κB/MAPK activation

Food Chem. 2013; 136(3-4): 1288-95.

Tominori Kimura, et al.

Stabilization of human interferon-α1 mRNA by its antisense RNA

Cell Mol Life Sci. 2013; 70(8): 1451-67.

Won-Woo Lee, et al.

Active Hexose Correlated Compound promotes T helper (Th) 17 and 1 cell responses via inducing IL-1β production from monocytes in humans

Cell Immunol. 2012; 275(1-2): 19-23.

Zhinan Yin, et al.

Effects of active hexose correlated compound on frequency of CD4+ and CD8+ T cells producing interferon-γ and/or tumor necrosis factor-α in healthy adults

Hum Immunol. 2010; 71(12): 1187-90.

Naoyoshi Terakawa, et al.

Immunological Effect of Active Hexose Correlated Compound (AHCC) in Healthy Volunteers: A Double-Blind, Placebo-Controlled Trial

Nutr Cancer. 2008; 60(5): 643-51.

Mari Kogiso, et al.

Active Hexose Correlated Compound and T Cell Response in Hind-Limb-Unloaded BALB/c Mice

Int J Surg. 2015; 2(5): 32-38.

Roghayeh Shahbazi, et al.

Lentinula edodes Cultured Extract and Rouxiella badensis subsp. acadiensis (Canan SV-53) Intake Alleviates Immune Deregulation and Inflammation by Modulating Signaling Pathways and Epigenetic Mechanisms

Int. J. Mol. Sci. 2023, 24(19), 14610

Katie M Love, et al.

A natural immune modulator attenuates stress hormone and catecholamine concentrations in polymicrobial peritonitis

J Trauma Acute Care Surg. 2013; 74(6): 1411-8.

Abeed H Chowdhury, et al.

Modulation of T Regulatory and Dendritic Cell Phenotypes Following Ingestion of Bifidobacterium longum, AHCC® and Azithromycin in Healthy Individuals

Nutrients. 2019; 11(10): 2470.

Borja Ocón, et al.

Active hexose-correlated compound and Bifidobacterium longum BB536 exert symbiotic effects in experimental colitis

Eur J Nutr. 2013; 52(2): 457-66.

Andrea Del Buono, et al.

Polysaccharide from Lentinus edodes for Integrative Cancer Treatment: Immunomodulatory Effects on Lymphocyte Population

World Cancer Research Journal. 2016; 3 (1): e652.

Zhiyun Cao, et al.

Active hexose correlated compound potentiates the antitumor effects of low-dose 5-fluorouracil through modulation of immune function in hepatoma 22 tumor-being mice

Nutr Res Pract. 2015; 9(2): 129-36.

Victoria L Gau, et al.

Potential Role for Active Hexose Correlated Compound (AHCC) in Treatment of Recurrent Respiratory Papillomatosis

J Voice. 2022; 36(4): 441-442.

Judith A Smith, et al.

AHCC® Supplementation to Support Immune Function to Clear Persistent Human Papillomavirus Infections

Front Oncol. 2022; 12: 881902.

Manami Misu, et al.

Clinical Effects of AHCC® on High-risk Human Papillomavirus Infection and Secretory IgA

Japanese Pharmacology & Therapeutics. 2019; 47(11): 1921-1928.

Judith A Smith, et al.

From Bench to Bedside: Evaluation of AHCC Supplementation to Modulate the Host Immunity to Clear High-Risk Human Papillomavirus Infections

Front Oncol. 2019; 9: 173.

Tian Wang, et al.

Oral Supplementation with AHCC®, A Standardized Extract of Cultured Lentinula edodes Mycelia, Enhances Host Resistance Against SARS-CoV-2 Infection

Pathogens. 2023; 12(4): 554.

Takeshi Katsuki, et al.

COVID-19 Pathology and Countermeasures ─Necessity of Severity Prevention Self-care─

Journal of Japan Health Medicine Association, 29(2): 142-152, 2020

Ali A. Rabaan, et al.

SARS-CoV-2/COVID-19 and advances in developing potential therapeutics and vaccines to counter this emerging pandemic

Ann Clin Microbiol Antimicrob. 2020; 19(1): 40

Brooke E Roman, et al.

Short-term supplementation with Active Hexose Correlated Compound (AHCC) improves the antibody response to influenza B vaccine

Nutr Res. 2013; 33(1): 12-7.

Shoko Nogusa, et al.

Low-dose supplementation with active hexose correlated compound improves the immune response to acute influenza infection in C57BL/6 mice

Nutr Res. 2009; 29(2): 139-43.

Beatriz López-Cauce, et al.

Lentinula edodes extract increases goblet cell number and Muc2 expression in an intestinal inflammatory model of Trichinella spiralis infection

Biomed Pharmacother. 2022; 150: 112937.

Mireia Tena-Garitaonaindia, et al.

A Standardized Extract of Lentinula edodes Cultured Mycelium Inhibits Pseudomonas aeruginosa Infectivity Mechanisms

Front Microbiol. 2022; 13: 814448.

Barry W Ritz

Supplementation with active hexose correlated compound increases survival following infectious challenge in mice

Nutr Rev. 2008; 66(9): 526-31.

María-Dolores Tabar, et al.

Leishmaniosis in a cat with chronic diarrhea as the only clinical manifestation

J Vet Intern Med. 2022; 36(2): 753-757.

María Auxiliadora Dea-Ayuela, et al.

Nucleotides and AHCC Enhance Th1 Responses In Vitro in Leishmania-Stimulated/Infected Murine Cells

Molecules. 2020; 25(17): 3918.

Rodolfo Oliveira Leal, et al.

Granulomatous rhinitis secondary to feline leishmaniosis: report of an unusual presentation and therapeutic complications

JFMS Open Rep. 2018; 4(2): 2055116918811374.

Sergi Segarra, et al.

Prevention of disease progression in Leishmania infantum-infected dogs with dietary nucleotides and Active Hexose Correlated Compound

Parasit Vectors. 2018; 11(1): 103.

Sergi Segarra, et al.

Randomized, allopurinol-controlled trial of the effects of dietary nucleotides and active hexose correlated compound in the treatment of canine leishmaniosis

Vet Parasitol. 2017; 239: 50-56.

Sergi Segarra.

Nutritional Modulation of the Immune Response Mediated by Nucleotides in Canine Leishmaniosis

Microorganisms. 2021; 9(12): 2601.

John Salerno, et al.

A Pilot Open-Label Study Assessing the Effects of AHCC® Supplementation on Lyme Disease Patients

Bioactive Compounds in Health and Disease. 2019; 2(11): 221-229.

Masaki Fujita, et al.

Attenuation of Pulmonary Mycobacterium Avium Disease by Active Hexose Correlated Compound (AHCC) in Mice

J Nutr Disorders Ther. 2015; 5: 4.

Shuhui Wang, et al.

Oral Administration of Active Hexose Correlated Compound Enhances Host Resistance to West Nile Encephalitis in Mice

J Nutr. 2009; 139(3): 598-602.

Hernan Aviles, et al.

Active hexose correlated compound activates immune function to decrease bacterial load in a murine model of intramuscular infection

Am J Surg. 2008; 195(4): 537-45.

Tesfaye Belay, et al.

Active Hexose-Correlated Compound Restores Gene Expression and Protein Secretion of Protective Cytokines of Immune Cells in a Murine Stress Model during Chlamydia muridarum Genital Infection

Infect Immun. 2021; 89(5): e00786-20.

Tesfaye Belay, et al.

Active Hexose Correlated Compound Activates Immune Function to Decrease Chlamydia trachomatis Shedding in a Murine Stress Model

J Nutr Med Diet Care. 2015; 1(1): JNMDC-1-006.

Alba Pérez-Cantero, et al.

Increased Efficacy of Oral Fixed-Dose Combination of Amphotericin B and AHCC® Natural Adjuvant against Aspergillosis

Pharmaceutics. 2019; 11(9): 456.

Sayam Thaiudom, et al.

A study of the efficacy of Active Hexose Correlated Compound (AHCC) in the treatment of chronic Hepatitis C patients at Phramongkutklao Hospital

The Medical News (Thailand). 2010; 325: 13-16.

Hiroaki Yanagimoto, et al.

Efficacy of Lentinula edodes Mycelia Extract on Chemotherapy-Related Tasted Disorders in Pancreatic Cancer Patients

Nutr Cancer. 2023; 75(1): 236-246.

Daisuke Hashimoto, et al.

Efficacy of active hexose correlated compound on survival of patients with resectable/borderline resectable pancreatic cancer: a study protocol for a double-blind randomized phase II study

Trials. 2022; 23(1): 135.

Yasuhiro Kuramitsu, et al.

Analysis of Cancer-Related Proteins Using Electrophoresis and Its Clinical Application

Electrophoresis Letters. 2021; 65(2): 23-27.

Shajedul Islam, et al.

A standardized extract of cultured Lentinula edodes mycelia downregulates cortactin in gemcitabine‑resistant pancreatic cancer cells

Oncol Lett. 2021; 22(3): 654.

Daisuke Hashimoto, et al.

Nutritional impact of active hexose-correlated compound for patients with resectable or borderline-resectable pancreatic cancer treated with neoadjuvant therapy

Surg Today. 2021; 51(11): 1872-1876.

Anarkhuu Bold-Erdene, et al.

Clinical outcomes of active hexose correlated compound (AHCC®) and its effect on chemotherapy related adverse events in patients with unresectable pancreatic cancer

Diagnosis. 2018; 83(3): 56-60.

Keisuke Kuhara, et al.

CUB Domain-containing Protein 1 (CDCP1) Is Down-regulated by Active Hexose-correlated Compound in Human Pancreatic Cancer Cells

Anticancer Res. 2018; 38(11): 6107-6111.

Hiroaki Yanagimoto, et al.

Alleviating effect of Active Hexose Correlated Compound (AHCC) on chemotherapy-related adverse events in patients with unresectable pancreatic ductal adenocarcinoma

Nutr Cancer. 2016; 68(2): 234-40.

Masayuki Tokunaga, et al.

Active Hexose-correlated Compound Down-regulates Heat Shock Factor 1, a Transcription Factor for HSP27, in Gemcitabine-resistant Human Pancreatic Cancer Cells

Anticancer Res. 2015; 35(11): 6063-7.

Junya Nawata, et al.

Active Hexose-correlated Compound Down-regulates Sex-determining Region Y-box 2 of Pancreatic Cancer Cells

Anticancer Res. 2014; 34(9): 4807-11.

Shigeyuki Suenaga, et al.

Active Hexose-correlated Compound Down-regulates HSP27 of Pancreatic Cancer Cells, and Helps the Cytotoxic Effect of Gemcitabine

Anticancer Res. 2014; 34(1): 141-6.

Toshiya Kamiyama, et al.

Preventing Recurrence of Hepatocellular Carcinoma After Curative Hepatectomy With Active Hexose-correlated Compound Derived From Lentinula edodes Mycelia

Integr Cancer Ther. 2022; 21: 15347354211073066.

Zhiyun Cao, et al.

Active hexose correlated compound potentiates the antitumor effects of low-dose 5-fluorouracil through modulation of immune function in hepatoma 22 tumor-being mice

Nutr Res Pract. 2015; 9(2): 129-36.

Koji Wakame, et al.

Long-term administration of Active Hexose Correlated Compound as a dietary supplement to a patient after breast cancer surgery and chemotherapy: A case report

Integr Cancer Sci Ther. 2017; 4(1).

Mehran Haidari, et al.

Disruption of endothelial adherens junction by invasive breast cancer cells is mediated by reactive oxygen species and is attenuated by AHCC.

Life Sci. 2013; 93(25-26): 994-1003.

Sho Hangai, et al.

Effect of Active Hexose-Correlated Compound in Women Receiving Adjuvant Chemotherapy for Breast Cancer: A Retrospective Study

J Altern Complement Med. 2013; 19(11): 905-10.

Yoichi Matsui, et al.

Retrospective Study in Breast Cancer Patients Supplemented with AHCC

Inte J Integr Oncol. 2009; 3(2): 12-16.

Daisuke Nakamoto, et al.

Active Hexose Correlated Compound (AHCC) Alleviates Gemcitabine-Induced Hematological Toxicity in Non-Tumor-Bearing Mice

Intern J Clin Med. 2012; 3: 361-367.

Kota Shigama, et al.

Alleviating effect of active hexose correlated compound (AHCC) for anticancer drug-induced side effects in non-tumor-bearing mice

J Exp Ther Oncol. 2009; 8(1): 43-51.

Buxiang Sun, et al.

The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury in rodents

Cancer Epidemiol. 2009; 33(3-4): 293-9.

Jin Young Choia, et al.

Active Hexose Correlated Compound (AHCC) Inhibits the Proliferation of Ovarian Cancer Cells by Suppressing Signal Transducer and Activator of Transcription 3 (STAT3) Activation

Nutr Cancer. 2018; 70(1): 109-115.

Wineeya Suknikhom, et al.

The Effects of Active Hexose Correlated Compound (AHCC) on Levels of CD4+ and CD8+ in Patients with Epithelial Ovarian Cancer or Peritoneal Cancer Receiving Platinum Based Chemotherapy

Asian Pac J Cancer Prev. 2017; 18(3): 633-638.

Shin-Nosuke Yamashita, et al.

Down-regulating Effect of a Standardized Extract of Cultured Lentinula edodes mycelia on Cortactin in Prostate Cancer Cells Is Dependent on Malignant Potential

Anticancer Res. 2023; 43(3): 1159-1166.

Yoshiteru Sumiyoshi, et al.

Dietary Administration of Mushroom Mycelium Extracts in Patients with Early Stage Prostate Cancers Managed Expectantly: A Phase II Study

Jpn J Clin Oncol. 2010; 40(10): 967-72.

Jeffrey Turner, et al.

Dramatic prostate-specific antigen response with activated hemicellulose compound in metastatic castration-resistant prostate cancer

Anticancer Drugs. 2009; 20(3): 215-6.

Francesca Paganelli, et al.

The Combination of AHCC and ETAS Decreases Migration of Colorectal Cancer Cells, and Reduces the Expression of LGR5 and Notch1 Genes in Cancer Stem Cells: A Novel Potential Approach for Integrative Medicine

Pharmaceuticals. 2021; 14(12): 1325.

Maiko Takahashi, et al.

Activation of NF-E2 p45-related factor-2 transcription and inhibition of intestinal tumor development by AHCC, a standardized extract of cultured Lentinula edodes mycelia

J Clin Biochem Nutr. 2019; 65(3): 203-208.

Hong-Jai Park, et al.

AHCC®, a standardized extract of cultured Lentinula edodes mycelia, promotes the anti-tumor effect of dual immune checkpoint blockade effect in murine colon cancer

Front Immunol. 2022; 13: 875872.

Reiki Ishizuka, et al.

Personalized Cancer Therapy for Stage IV Lung Cancer: Combined Use of Active Hexose Correlated Compound and Genistein Concentrated Polysaccharide

Pers Med Univers. 2012; 1(1): 39-44.

Reiki Ishizuka, et al.

Review of Cancer Therapy with AHCC(R) and GCP(R); The Long-Term Follow-Up over 12 Years for Stage IV (M1) Cancer of the Lung and the Breast

International Journal of Integrative Medicine. 2010; 2(1): 98-111.

Lata Mathew, et al.

Evaluation of Active Hexose Correlated Compound (AHCC) in Combination With Anticancer Hormones in Orthotopic Breast Cancer Models

Integr Cancer Ther. 2017; 16(3): 300-307.

Rodney J Hunter, et al.

Evaluation of active hexose correlated compound (AHCC) in combination with pegylated liposomal doxorubicin for treatment of ovarian cancer

Int J Appl Res Nat Prod. 2011; 4(3): 6-14.

Andrea Del Buono, et al.

Polysaccharide from Lentinus edodes for Integrative Cancer Treatment: Immunomodulatory Effects on Lymphocyte Population

World Cancer Research Journal. 2016; 3 (1): e652.

Yusai Kawaguchi

Improved Survival of Patients with Gastric Cancer or Colon Cancer when treated with Active Hexose Correlated Compound (AHCC): Effect of AHCC on digestive system cancer

Natural Medicine Journal. 2009; 1(1).

Kavin Fatehchand, et al.

Active hexose-correlated compound enhances extrinsic-pathway-mediated apoptosis of Acute Myeloid Leukemic cells

PLoS One. 2017; 12(7): e0181729.

Dillip Kumar Parida, et al.

Integrating Complimentary and Alternative Medicine in Form of Active Hexose Correlated Compound (AHCC) in the Management of Head & Neck Cancer Patients

Intern J Clin Med. 2011; 2, 588-592.

Tamer A Badawi, et al.

Immunoprophylactic Effect of Active Hexose Correlated Compound on Normal and Induced Submandibular Salivary Gland Neoplasm in Albino Rats

Cairo Dental Journal. 2012; 28(1): 485-490.

Toshinori Ito, et al.

Reduction of Adverse Effects by a Mushroom Product, Active Hexose Correlated Compound (AHCC) in Patients with Advanced Cancer during Chemotherapy-The Significance of the Levels of HHV-6 DNA in Saliva as a Surrogate Biomarker during Chemotherapy.

Nutr Cancer. 2014; 66(3): 377-82.

Émilie A Graham, et al.

MicroRNA signature in the chemoprevention of functionally-enriched stem and progenitor pools (FESPP) by Active Hexose Correlated Compound (AHCC)

Cancer Biol Ther. 2017; 18(10): 765-774.

Bruna Corradetti, et al.

Bioactive Immunomodulatory Compounds: A Novel Combinatorial Strategy for Integrated Medicine in Oncology? BAIC Exposure in Cancer Cells

Integr Cancer Ther. 2019; 18: 1534735419866908.

Rosa Mistica Ignacio, et al.

Therapeutic effect of Active Hexose-Correlated Compound (AHCC) combined with CpG-ODN (oligodeoxynucleotide) in B16 melanoma murine model

Cytokine. 2015; 76(2): 131-137.

Zaure Zhaparkhanova, et al.

The effect of active hexose correlated compound on (multi) nodular euthyroid goiter: A double-blind placebo-controlled study

J Clin Med Kaz. 2021; 18(2): 66-71.

Yoshito Tanaka, et al.

Adenosine, a hepato-protective component in active hexose correlated compound: Its identification and iNOS suppression mechanism

Nitric Oxide. 2014; 40: 75-86.

Kosuke Matsui, et al.

Active Hexose Correlated Compound Inhibits the Expression of Proinflammatory Biomarker iNOS in Hepatocytes

Eur Surg Res. 2011; 47(4): 274-83.

Tadayoshi Okumura, et al.

Inhibition of iNOS induction by functional food AHCC (Screening of food with “hepatoprotective effect” using in vitro hepatocytes)

Journal of the Japanese Society of Food Engineering. 2010; 30(3): 100-106.

Rachel E. Carlson, et al.

Screening for potential pathways of drug-supplement interactions between AHCC® and common medications

IJNF. 2018; 4(5): 32-36.

Larry W Coffer, et al.

Evaluation of active hexose correlated compound (AHCC) on phase II drug metabolism pathways and the implications for supplement-drug interactions

J Integr Oncol. 2015; doi:10.4172/2329-6771.1000142.

Claire M Mach, et al.

Evaluation of Active Hexose Correlated Compound Hepatic Metabolism and Potential for Drug Interactions with Chemotherapy Agents

J Soc Integr Oncol. 2008; 6(3): 105-9.

Marie-Francoise Doursout, et al.

Active hexose correlated compound modulates LPS-induced hypotension and gut injury in rats

Int Immunopharmacol. 2016; 39: 280-286.

Cristina Mascaraque, et al.

Active hexose correlated compound exerts therapeutic effects in lymphocyte driven colitis

Mol Nutr Food Res. 2014; 58(12): 2379-82.

Jun Takanari, et al.

Effects of AHCC® on Immune and Stress Responses in Healthy Individuals

J Evid Based Integr Med. 2018; 23: 2156587218756511.

Natalia V Mikhailichenko, et al.

An open label trial of a standardized extract of cultured Lentinula edodes mycelia (ECLM) in children with refractory epilepsy

FFHD. 2019; 9(3): 145-156.

Young-Ju Song, et al.

AHCC Supplementation Attenuates Muscle Atrophy via Akt Activation in Hindlimb-suspended Rat

Biotechnol Bioprocess Eng. 2019; 24: 476-482.

Yosuke Ueyama, et al.

Active Hexose Correlated Compound Has Protective Effects in Ischemia-Reperfusion Injury of the Rat Small Intestine

J Surg Res. 2019; 243: 265-273.

Richi Nakatake, et al.

Protective effects of active hexose correlated compound in a rat model of liver injury after hepatectomy

FFHD. 2016; 6(11): 702-717.

Tetsuya Okuyama, et al.

Active Hexose Correlated Compound Extends the Lifespan and Increases the Thermotolerance of Nematodes

FFHD. 2013; 3(6):166-182.

Koji Wakame, et al.

DNA microarray analysis of gene expression changes in ICR mouse liver following treatment with active hexose correlated compound

Integr Mol Med. 2016; 3(3): 739-744.

Hyangkyoung Kim, et al.

Effect of Active Hexose Correlated Compound (AHCC) in Alcohol-Induced Liver Enzyme Elevation

J Nutr Sci Vitaminol. 2014; 60(5): 348-56.

Hajime Fujii, et al.

Genotoxicity and subchronic toxicity evaluation of Active Hexose Correlated Compound (AHCC)

Regul Toxicol Pharmacol. 2011; 59(2): 237-50.

Takehito Miura

Unwellness and Functional Foods: The Expected Role of Pharmacies

J Jpn Mibyou Assoc. 2022; 28(2): 43-48.

Jun-Young Choi

Complementary Therapy for Improvement of Quality of Life in Cancer Patients

J Korean Med Assoc. 2008; 51(5): 435-448.

Min Sun Shin, et al.

The Effects of AHCC®, a Standardized Extract of Cultured Lentinura edodes Mycelia, on Natural Killer and T Cells in Health and Disease: Reviews on Human and Animal Studies

J Immunol Res. 2019; 2019: 3758576

Hiroshi Nishioka, et al.

Potentiating action of AHCC on natural immunity

Medical Science Digest. 2009; 35(6): 241-244.

Philippa J Cheetham, et al.

Diet and prostate cancer – a holistic approach to management

Arch Esp Urol. 2011; 64(8): 720-34.

Francesco Di Pierro, et al.

Possible therapeutic role of a highly standardized mixture of active compounds derived from cultured Lentinula edodes mycelia (AHCC) in patients infected with 2019 novel coronavirus

Minerva Gastroenterol Dietol. 2020; 66(2): 172-176.

Manami Misu, et al.

Various functions of AHCC® – Case Report

New Food Industry. 2017; 59(2): 14-21.

Yutaka Horiuchi, et al.

Complementary and Alternative Medicine and AHCC®, GCP® in Companion Animals

Companion Animal Practice. 2012; 4: 53-57.

Takashi Nishizawa, et al.

Alpha Glucan (AHCC Liquid) Activates Macrophages More than Beta Glucan – Prospects for Basidiomycetes

Companion Animal Practice. 2011 Apr.

Mamoru Onuma, et al.

The supplementation therapy of caine dermatology in my hospital

Japanese Journal of Small Animal Practice. 2008; 27(6): 340-346.

Mikio Nishizawa, et al.

Assessment of anti-inflammatory effects of Japanese Kampo medicine versus functional foods

FFHD. 2019; 9(2): 79-91.

Hiroshi Nishioka, et al.

Various functions of a standardized extract of cultured Lentinula edodes mycelia (AHCC®)

Medical Science Digest. 2019; 45(2): 127-130.

Koji Wakame

Research and functional development of basidiomycete culture extracts

Agricultural biotechnology. 2017; 1(4): 438-442.

Robert M Hackman, et al.

Forecasting Nutrition Research in 2020

J Am Coll Nutr. 2014; 33(4): 340-6.

Catherine Ulbricht, et al.

An Evidence-Based Systematic Review of Active Hexose Correlated Compound (AHCC) by the Natural Standard Research Collaboration

J Diet Suppl. 2013; 10(3): 264-308.

Yasuo Kamiyama

AHCC: basic and clinical research

Journal of the society tropical resources technologists. 2011; 27(1): 1-8.

Shinil K Shah, et al.

An Evidence-Based Review of a Lentinula edodes Mushroom Extract as Complementary Therapy in the Surgical Oncology Patient

J Parenter Enteral Nutr. 2011; 35(4): 449-58.

Barry W Ritz

Active Hexose Correlated Compound (AHCC) and Immune Outcomes in Humans: A Review

Natural Medicine Journal. 2011; 3(1): 3-7.

Takehito Miura, et al.

Basic and Clinical Studies on Active Hexose Correlated Compound

Biotechnology in Functional Foods and Nutraceuticals. 2010: 51-58.

Takehito Miura, et al.

Basic and Clinical Studies on AHCC —Recent Topics—

Japanese Journal of Complementary and Alternative Medicine. 2009; 6(1): 1-7.

Kentaro Kitadate

Augmentation of Anticancer Activity and Attenuation of Side Effect by AHCC

FOOD Style 21. 2008; 132: 69-72.