論文

Roghayeh Shahbazi, et al.

Lentinula edodes Cultured Extract and Rouxiella badensis subsp. acadiensis (Canan SV-53) Intake Alleviates Immune Deregulation and Inflammation by Modulating Signaling Pathways and Epigenetic Mechanisms

Int J Mol Sci. 2023; 24(19): 14610.

Bruna De Felice, et al.

Effect of beta- and alpha-glucans on immune modulating factors expression in enterocyte-like Caco-2 and goblet-like LS 174T cells

Int J Biol Macromol. 2020; 153: 600-607.

Jean‑François Mallet, et al.

Active Hexose Correlated Compound (AHCC) promotes an intestinal immune response in BALB/c mice and in primary intestinal epithelial cell culture involving toll-like receptors TLR-2 and TLR-4

Eur J Nutr. 2016; 55(1): 139-46.

Loretta Olamigoke, et al.

AHCC Activation and Selection of Human Lymphocytes via Genotypic and Phenotypic Changes to an Adherent Cell Type: A Possible Novel Mechanism of T Cell Activation

Evid Based Complement Alternat Med. 2015; 508746.

高成準ら

Effects of Active Hexose Correlated Compound on the Seasonal Variations of Immune Competence in Healthy Subjects

J Evid Based Complementary Altern Med. 2015; 20(1): 28-34.

Mari Kogiso, et al.

Active Hexose Correlated Compound and T Cell Response in Hind-Limb-Unloaded BALB/c Mice

Int J Surg. 2015; 2(5): 32-38.

Abdelali Daddaoua, et al.

The nutritional supplement Active Hexose Correlated Compound (AHCC) has direct immunomodulatory actions on intestinal epithelial cells and macrophages involving TLR/MyD88 and NF-κB/MAPK activation

Food Chem. 2013; 136(3-4): 1288-95.

木村富紀ら

Stabilization of human interferon-α1 mRNA by its antisense RNA

Cell Mol Life Sci. 2013; 70(8): 1451-67.

Won-Woo Lee, et al.

Active Hexose Correlated Compound promotes T helper (Th) 17 and 1 cell responses via inducing IL-1β production from monocytes in humans

Cell Immunol. 2012; 275(1-2): 19-23.

Zhinan Yin, et al.

Effects of active hexose correlated compound on frequency of CD4+ and CD8+ T cells producing interferon-γ and/or tumor necrosis factor-α in healthy adults

Hum Immunol. 2010; 71(12): 1187-90.

寺川直良ら

Immunological Effect of Active Hexose Correlated Compound (AHCC) in Healthy Volunteers: A Double-Blind, Placebo-Controlled Trial

Nutr Cancer. 2008; 60(5): 643-51.

Francisco Karkow, et al.

AHCC® in Sjögren’s Disease: One Bold Therapeutic Hypothesis

EC Microbiol. 2020; 16(1).

Zaure Zhaparkhanova, et al.

自己免疫性甲状腺疾患における栄養免疫療法：予備試験結果

内分泌学速報（ロシア語）. 2018; 2(50): 23-27.

Katie M Love, et al.

A natural immune modulator attenuates stress hormone and catecholamine concentrations in polymicrobial peritonitis

J Trauma Acute Care Surg. 2013; 74(6): 1411-8.

Borja Ocón, et al.

Active hexose-correlated compound and Bifidobacterium longum BB536 exert symbiotic effects in experimental colitis

Eur J Nutr. 2013; 52(2): 457-66.

Abeed H Chowdhury, et al.

Modulation of T Regulatory and Dendritic Cell Phenotypes Following Ingestion of Bifidobacterium longum, AHCC® and Azithromycin in Healthy Individuals

Nutrients. 2019; 11(10): 2470.

Andrea Del Buono, et al.

Polysaccharide from Lentinus edodes for Integrative Cancer Treatment: Immunomodulatory Effects on Lymphocyte Population

World Cancer Research Journal. 2016; 3 (1): e652.

Zhiyun Cao, et al.

Active hexose correlated compound potentiates the antitumor effects of low-dose 5-fluorouracil through modulation of immune function in hepatoma 22 tumor-being mice

Nutr Res Pract. 2015; 9(2): 129-36.

Ufuk Atlihan, et al.

Evaluation of the Efficacy of Active Hexose Correlated Compound as an Adjuvant in Reducing Recurrence After Condyloma Cauterization

Medicina. 2025; 61(4): 622.

Zehra Kececi, et al.

New approaches in Human Papillomavirus (HPV) treatment: Active Hexose-Related Compound (AHCC®)

J. Fac. Pharm. Ankara. 2024; 48(2): 714-726.

Nizar A Khamjan, et al.

Natural and synthetic drugs and formulations for intravaginal HPV clearance

J Infect Public Health. 2023; 16(9): 1471-1480.

Victoria L Gau, et al.

Potential Role for Active Hexose Correlated Compound (AHCC) in Treatment of Recurrent Respiratory Papillomatosis

J Voice. 2022; 36(4): 441-442.

Judith A Smith, et al.

AHCC® Supplementation to Support Immune Function to Clear Persistent Human Papillomavirus Infections

Front Oncol. 2022; 12: 881902.

三栖茉奈美ら

ハイリスク型ヒトパピローマウイルス感染と分泌型IgA に対するAHCC®の臨床効果

薬理と治療. 2019; 47(11): 1921-1928.

Judith A Smith, et al.

From Bench to Bedside: Evaluation of AHCC Supplementation to Modulate the Host Immunity to Clear High-Risk Human Papillomavirus Infections

Front Oncol. 2019; 9: 173.

Ankita Singh, et al.

Oral Supplementation with AHCC®, A Standardized Extract of Cultured Lentinula edodes Mycelia, Enhances Host Resistance Against SARS-CoV-2 Infection

Pathogens. 2023; 12(4): 554.

香月毅史ら

COVID-19の病理と対処法　─重症化予防セルフケアの必要性─

日本健康医学会雑誌 2020年29巻2号 p.142-152

Ali A Rabaan, et al.

SARS-CoV-2/COVID-19 and advances in developing potential therapeutics and vaccines to counter this emerging pandemic

Ann Clin Microbiol Antimicrob. 2020; 19(1): 40.

Brooke E Roman, et al.

Short-term supplementation with Active Hexose Correlated Compound (AHCC) improves the antibody response to influenza B vaccine

Nutr Res. 2013; 33(1): 12-7.

Shoko Nogusa, et al.

Low-dose supplementation with active hexose correlated compound improves the immune response to acute influenza infection in C57BL/6 mice

Nutr Res. 2009; 29(2): 139-43.

Beatriz López-Cauce, et al.

Lentinula edodes extract increases goblet cell number and Muc2 expression in an intestinal inflammatory model of Trichinella spiralis infection

Biomed Pharmacother. 2022; 150: 112937.

Mireia Tena-Garitaonaindia, et al.

A Standardized Extract of Lentinula edodes Cultured Mycelium Inhibits Pseudomonas aeruginosa Infectivity Mechanisms

Front Microbiol. 2022; 13: 814448.

Barry W Ritz

Supplementation with active hexose correlated compound increases survival following infectious challenge in mice

Nutr Rev. 2008; 66(9): 526-31.

Guadalupe Miró, et al.

New immunomodulatory treatment protocol for canine leishmaniosis reduces parasitemia and proteinuria

PLoS Negl Trop Dis. 2024; 18(12): e0012712.

Annalisa Previti, et al.

Trends and Gaps in the Scientific Literature about the Effects of Nutritional Supplements on Canine Leishmaniosis

Pathogens. 2024; 13(10): 901.

María-Dolores Tabar, et al.

Leishmaniosis in a cat with chronic diarrhea as the only clinical manifestation

J Vet Intern Med. 2022; 36(2): 753-757.

Sergi Segarra.

Nutritional Modulation of the Immune Response Mediated by Nucleotides in Canine Leishmaniosis

Microorganisms 2021; 9(12), 2601

María Auxiliadora Dea-Ayuela, et al.

Nucleotides and AHCC Enhance Th1 Responses In Vitro in Leishmania-Stimulated/Infected Murine Cells

Molecules. 2020; 25(17): 3918.

Rodolfo Oliveira Leal, et al.

Granulomatous rhinitis secondary to feline leishmaniosis: report of an unusual presentation and therapeutic complications

JFMS Open Rep. 2018; 4(2): 2055116918811374.

Sergi Segarra, et al.

Prevention of disease progression in Leishmania infantum-infected dogs with dietary nucleotides and Active Hexose Correlated Compound

Parasit Vectors. 2018; 11(1): 103.

Sergi Segarra, et al.

Randomized, allopurinol-controlled trial of the effects of dietary nucleotides and active hexose correlated compound in the treatment of canine leishmaniosis

Vet Parasitol. 2017; 239: 50-56.

John Salerno, et al.

A Pilot Open-Label Study Assessing the Effects of AHCC® Supplementation on Lyme Disease Patients

Bioactive Compounds in Health and Disease. 2019; 2(11): 221-229.

藤田昌樹ら

Attenuation of Pulmonary Mycobacterium Avium Disease by Active Hexose Correlated Compound (AHCC) in Mice

J Nutr Disorders Ther. 2015; 5: 4.

Shuhui Wang, et al.

Oral Administration of Active Hexose Correlated Compound Enhances Host Resistance to West Nile Encephalitis in Mice

J Nutr. 2009; 139(3): 598-602.

Hernan Aviles, et al.

Active hexose correlated compound activates immune function to decrease bacterial load in a murine model of intramuscular infection

Am J Surg. 2008; 195(4): 537-45.

Tesfaye Belay, et al.

Active Hexose-Correlated Compound Restores Gene Expression and Protein Secretion of Protective Cytokines of Immune Cells in a Murine Stress Model during Chlamydia muridarum Genital Infection

Infect Immun. 2021; 89(5): e00786-20.

Tesfaye Belay, et al.

Active Hexose Correlated Compound Activates Immune Function to Decrease Chlamydia trachomatis Shedding in a Murine Stress Model

J Nutr Med Diet Care. 2015; 1(1): JNMDC-1-006.

Alba Pérez-Cantero, et al.

Increased Efficacy of Oral Fixed-Dose Combination of Amphotericin B and AHCC® Natural Adjuvant against Aspergillosis

Pharmaceutics. 2019; 11(9): 456.

Sayam Thaiudom, et al.

A study of the efficacy of Active Hexose Correlated Compound (AHCC) in the treatment of chronic Hepatitis C patients at Phramongkutklao Hospital

The Medical News (Thailand). 2010; 325: 13-16.

足立成基ら

Continuous Ingestion of a Standardized Extract of Cultured Lentinula edodes Mycelia Suppresses Spontaneous Carcinogenesis in a Murine Model

Biol Pharm Bull. 2025; 48(5): 687-693.

柳本泰明ら

Efficacy of Lentinula edodes Mycelia Extract on Chemotherapy-Related Tasted Disorders in Pancreatic Cancer Patients

Nutr Cancer. 2023; 75(1): 236-246.

橋本大輔ら

Efficacy of active hexose correlated compound on survival of patients with resectable/borderline resectable pancreatic cancer: a study protocol for a double-blind randomized phase II study

Trials. 2022; 23(1): 135.

藏滿保宏ら

電気泳動法を用いた癌関連蛋白質の解析と臨床への応用

電気泳動. 2021; 65(2): 23-27.

Shajedul Islam, et al.

A standardized extract of cultured Lentinula edodes mycelia downregulates cortactin in gemcitabine‑resistant pancreatic cancer cells

Oncol Lett. 2021; 22(3): 654.

橋本大輔ら

Nutritional impact of active hexose-correlated compound for patients with resectable or borderline-resectable pancreatic cancer treated with neoadjuvant therapy

Surg Today. 2021; 51(11): 1872-1876.

Anarkhuu Bold-Erdene, et al.

Clinical outcomes of active hexose correlated compound (AHCC®) and its effect on chemotherapy related adverse events in patients with unresectable pancreatic cancer

Diagnosis. 2018; 83(3): 56-60.

久原啓資ら

CUB Domain-containing Protein 1 (CDCP1) Is Down-regulated by Active Hexose-correlated Compound in Human Pancreatic Cancer Cells

Anticancer Res. 2018; 38(11): 6107-6111.

柳本泰明ら

Alleviating effect of Active Hexose Correlated Compound (AHCC) on chemotherapy-related adverse events in patients with unresectable pancreatic ductal adenocarcinoma

Nutr Cancer. 2016; 68(2): 234-40.

徳永雅之ら

Active Hexose-correlated Compound Down-regulates Heat Shock Factor 1, a Transcription Factor for HSP27, in Gemcitabine-resistant Human Pancreatic Cancer Cells

Anticancer Res. 2015; 35(11): 6063-7.

縄田純也ら

Active Hexose-correlated Compound Down-regulates Sex-determining Region Y-box 2 of Pancreatic Cancer Cells

Anticancer Res. 2014; 34(9): 4807-11.

末永成之ら

Active Hexose-correlated Compound Down-regulates HSP27 of Pancreatic Cancer Cells, and Helps the Cytotoxic Effect of Gemcitabine

Anticancer Res. 2014; 34(1): 141-6.

神山俊哉ら

Preventing Recurrence of Hepatocellular Carcinoma After Curative Hepatectomy With Active Hexose-correlated Compound Derived From Lentinula edodes Mycelia

Integr Cancer Ther. 2022; 21: 15347354211073066.

Zhiyun Cao, et al.

Active hexose correlated compound potentiates the antitumor effects of low-dose 5-fluorouracil through modulation of immune function in hepatoma 22 tumor-being mice

Nutr Res Pract. 2015; 9(2): 129-36.

Hamed Yasavoli-Sharahi, et al.

Edodes Cultured Extract Regulates Immune Stress During Puberty and Modulates MicroRNAs Involved in Mammary Gland Development and Breast Cancer Suppression

Cancer Med. 2024; 13(19): e70277.

松田実ら

健康補助食品で自己免疫性肝炎と癌組織の高度の変性が見られた乳癌の1例

日赤医学. 2019; 70(2): 378-381.

若命浩二ら

Long-term administration of Active Hexose Correlated Compound as a dietary supplement to a patient after breast cancer surgery and chemotherapy: A case report

Integr Cancer Sci Ther. 2017; 4(1).

Mehran Haidari, et al.

Disruption of endothelial adherens junction by invasive breast cancer cells is mediated by reactive oxygen species and is attenuated by AHCC.

Life Sci. 2013; 93(25-26): 994-1003.

半谷匠ら

Effect of Active Hexose-Correlated Compound in Women Receiving Adjuvant Chemotherapy for Breast Cancer: A Retrospective Study

J Altern Complement Med. 2013; 19(11): 905-10.

松井陽一ら

Retrospective Study in Breast Cancer Patients Supplemented with AHCC

Inte J Integr Oncol. 2009; 3(2): 12-16.

志鎌恒太ら

Alleviating effect of active hexose correlated compound (AHCC) for anticancer drug-induced side effects in non-tumor-bearing mice

J Exp Ther Oncol. 2009; 8(1): 43-51.

Buxiang Sun, et al.

The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury in rodents

Cancer Epidemiol. 2009; 33(3-4): 293-9.

中本大介ら

Active Hexose Correlated Compound (AHCC) Alleviates Gemcitabine-Induced Hematological Toxicity in Non-Tumor-Bearing Mice

Intern J Clin Med. 2012; 3: 361-367.

A. D’Orta, et al.

Management and treatment of sarcopenia in fifty patients receiving chemotherapy with AHCC (active hexose correlated compound)

WCRJ 2018; 5(2): e1089.

Jin Young Choia, et al.

Active Hexose Correlated Compound (AHCC) Inhibits the Proliferation of Ovarian Cancer Cells by Suppressing Signal Transducer and Activator of Transcription 3 (STAT3) Activation

Nutr Cancer. 2018; 70(1): 109-115.

Wineeya Suknikhom, et al.

The Effects of Active Hexose Correlated Compound (AHCC) on Levels of CD4+ and CD8+ in Patients with Epithelial Ovarian Cancer or Peritoneal Cancer Receiving Platinum Based Chemotherapy

Asian Pac J Cancer Prev. 2017; 18(3): 633-638.

山下新之助ら

Down-regulating Effect of a Standardized Extract of Cultured Lentinula edodes mycelia on Cortactin in Prostate Cancer Cells Is Dependent on Malignant Potential

Anticancer Res. 2023; 43(3): 1159-1166.

住吉義光ら

Dietary Administration of Mushroom Mycelium Extracts in Patients with Early Stage Prostate Cancers Managed Expectantly: A Phase II Study

Jpn J Clin Oncol. 2010; 40(10): 967-72.

Jeffrey Turner, et al.

Dramatic prostate-specific antigen response with activated hemicellulose compound in metastatic castration-resistant prostate cancer

Anticancer Drugs. 2009; 20(3): 215-6.

Francesca Paganelli, et al.

The Combination of AHCC and ETAS Decreases Migration of Colorectal Cancer Cells, and Reduces the Expression of LGR5 and Notch1 Genes in Cancer Stem Cells: A Novel Potential Approach for Integrative Medicine

Pharmaceuticals. 2021; 14(12): 1325.

Maiko Takahashi, et al.

Activation of NF-E2 p45-related factor-2 transcription and inhibition of intestinal tumor development by AHCC, a standardized extract of cultured Lentinula edodes mycelia

J Clin Biochem Nutr. 2019; 65(3): 203-208.

Hong-Jai Park, et al.

AHCC®, a standardized extract of cultured Lentinula edodes mycelia, promotes the anti-tumor effect of dual immune checkpoint blockade effect in murine colon cancer

Front Immunol. 2022; 13: 875872.

石塚玲器ら

Personalized Cancer Therapy for Stage IV Lung Cancer: Combined Use of Active Hexose Correlated Compound and Genistein Concentrated Polysaccharide

Pers Med Univers. 2012; 1(1): 39-44.

石塚玲器ら

Review of Cancer Therapy with AHCC(R) and GCP(R); The Long-Term Follow-Up over 12 Years for Stage IV (M1) Cancer of the Lung and the Breast

国際統合医学会誌. 2010; 2(1): 98-111.

Rodney J Hunter, et al.

Evaluation of active hexose correlated compound (AHCC) in combination with pegylated liposomal doxorubicin for treatment of ovarian cancer

Int J Appl Res Nat Prod. 2011; 4(3): 6-14.

Lata Mathew, et al.

Evaluation of Active Hexose Correlated Compound (AHCC) in Combination With Anticancer Hormones in Orthotopic Breast Cancer Models

Integr Cancer Ther. 2017; 16(3): 300-307.

Andrea Del Buono, et al.

Polysaccharide from Lentinus edodes for Integrative Cancer Treatment: Immunomodulatory Effects on Lymphocyte Population

World Cancer Research Journal. 2016; 3 (1): e652.

川口雄才

Improved Survival of Patients with Gastric Cancer or Colon Cancer when treated with Active Hexose Correlated Compound (AHCC): Effect of AHCC on digestive system cancer

Natural Medicine Journal. 2009; 1(1).

Giovanna Merchand-Reyes, et al.

Active Hexose-Correlated Compound Shows Direct and Indirect Effects against Chronic Lymphocytic Leukemia

Nutrients. 2023; 15(24): 5138.

Kavin Fatehchand, et al.

Active hexose-correlated compound enhances extrinsic-pathway-mediated apoptosis of Acute Myeloid Leukemic cells

PLoS One. 2017; 12(7): e0181729.

Dillip Kumar Parida, et al.

Integrating Complimentary and Alternative Medicine in Form of Active Hexose Correlated Compound (AHCC) in the Management of Head & Neck Cancer Patients

Intern J Clin Med. 2011; 2, 588-592.

Tamer A Badawi, et al.

Immunoprophylactic Effect of Active Hexose Correlated Compound on Normal and Induced Submandibular Salivary Gland Neoplasm in Albino Rats

Cairo Dental Journal. 2012; 28(1): 485-490.

伊藤壽記ら

Reduction of Adverse Effects by a Mushroom Product, Active Hexose Correlated Compound (AHCC) in Patients with Advanced Cancer during Chemotherapy-The Significance of the Levels of HHV-6 DNA in Saliva as a Surrogate Biomarker during Chemotherapy.

Nutr Cancer. 2014; 66(3): 377-82.

吉井鈴美ら

The Tumor Growth Inhibitory Effect of a Standardized Extract of Cultured Lentinula edodes Mycelia Using Patient Derived Xenograft Model

Biol Pharm Bull. 2024; 47(2): 532-538.

Émilie A Graham, et al.

MicroRNA signature in the chemoprevention of functionally-enriched stem and progenitor pools (FESPP) by Active Hexose Correlated Compound (AHCC)

Cancer Biol Ther. 2017; 18(10): 765-774.

Bruna Corradetti, et al.

Bioactive Immunomodulatory Compounds: A Novel Combinatorial Strategy for Integrated Medicine in Oncology? BAIC Exposure in Cancer Cells

Integr Cancer Ther. 2019; 18: 1534735419866908.

Rosa Mistica Ignacio, et al.

Therapeutic effect of Active Hexose-Correlated Compound (AHCC) combined with CpG-ODN (oligodeoxynucleotide) in B16 melanoma murine model

Cytokine. 2015; 76(2): 131-137.

Zaure Zhaparkhanova, et al.

The effect of aсtive hexose correlated compound on (multi) nodular euthyroid goiter: A double-blind placebo-controlled study

J Clin Med Kaz. 2021; 18(2): 66-71.

宇留島隼人ら

AHCC inhibited hepatic stellate cells activation by regulation of cytoglobin induction via TLR2-SAPK/JNK pathway and collagen production via TLR4-NF-κβ pathway

Am J Physiol Gastrointest Liver Physiol. 2024; 327(6): G741-G753.

田中義人ら

Adenosine, a hepato-protective component in active hexose correlated compound: Its identification and iNOS suppression mechanism

Nitric Oxide. 2014; 40: 75-86.

松井康輔ら

Active Hexose Correlated Compound Inhibits the Expression of Proinflammatory Biomarker iNOS in Hepatocytes

Eur Surg Res. 2011; 47(4): 274-83.

奥村忠芳ら

機能性食品AHCCによるiNOS誘導の阻害(in vitro肝細胞を用いた”肝保護効果”を持つ食品のスクリーニング)

食品加工技術. 2010; 30(3): 100-106.

Rachel E. Carlson, et al.

Screening for potential pathways of drug-supplement interactions between AHCC® and common medications

IJNF. 2018; 4(5): 32-36.

Larry W Coffer, et al.

Evaluation of active hexose correlated compound (AHCC) on phase II drug metabolism pathways and the implications for supplement-drug interactions

J Integr Oncol. 2015; doi:10.4172/2329-6771.1000142.

Claire M Mach, et al.

Evaluation of Active Hexose Correlated Compound Hepatic Metabolism and Potential for Drug Interactions with Chemotherapy Agents

J Soc Integr Oncol. Summer 2008; 6(3): 105-9.

Marie-Francoise Doursout, et al.

Active hexose correlated compound modulates LPS-induced hypotension and gut injury in rats

Int Immunopharmacol. 2016; 39: 280-286.

Cristina Mascaraque, et al.

Active hexose correlated compound exerts therapeutic effects in lymphocyte driven colitis

Mol Nutr Food Res. 2014; 58(12): 2379-82.

高成準ら

Effects of AHCC® on Immune and Stress Responses in Healthy Individuals

J Evid Based Integr Med. 2018; 23: 2156587218756511.

Natalia V Mikhailichenko, et al.

An open label trial of a standardized extract of cultured Lentinula edodes mycelia (ECLM) in children with refractory epilepsy

FFHD. 2019; 9(3): 145-156.

Young-Ju Song, et al.

AHCC Supplementation Attenuates Muscle Atrophy via Akt Activation in Hindlimb-suspended Rat

Biotechnol Bioprocess Eng. 2019; 24: 476-482.

中竹利知ら

Hepatoprotection of a Standardized Extract of Cultured Lentinula edodes Mycelia against Liver Injury Induced by Ischemia-Reperfusion and Partial Hepatectomy

Nutrients. 2024; 16(2): 256.

上山庸佑ら

Active Hexose Correlated Compound Has Protective Effects in Ischemia-Reperfusion Injury of the Rat Small Intestine

J Surg Res. 2019; 243: 265-273.

中竹利知ら

Protective effects of active hexose correlated compound in a rat model of liver injury after hepatectomy

FFHD. 2016; 6(11): 702-717.

奥山哲矢ら

Active Hexose Correlated Compound Extends the Lifespan and Increases the Thermotolerance of Nematodes

FFHD. 2013; 3(6):166-182.

若命浩二ら

DNA microarray analysis of gene expression changes in ICR mouse liver following treatment with active hexose correlated compound

Integr Mol Med. 2016; 3(3): 739-744.

Hyangkyoung Kim, et al.

Effect of Active Hexose Correlated Compound (AHCC) in Alcohol-Induced Liver Enzyme Elevation

J Nutr Sci Vitaminol. 2014; 60(5): 348-56.

Brian V Hong, et al.

Identification and Quantification of α-D-Glucopyranosyl-Isomaltol, α-D-Maltosyl-Isomaltol, and α-Glucan in AHCC® Cultured Mushroom Mycelia Extract

Int J Med Mushrooms. 2025; 27(6): 1-11.

藤井創ら

Genotoxicity and subchronic toxicity evaluation of Active Hexose Correlated Compound (AHCC)

Regul Toxicol Pharmacol. 2011; 59(2): 237-50.

三浦健人

未病と機能性食品　薬局に期待される役割

日本未病学会雑誌. 2022; 28(2): 43-48.

Jun-Young Choi

Complementary Therapy for Improvement of Quality of Life in Cancer Patients

J Korean Med Assoc. 2008; 51(5): 435-448.

Min Sun Shin, et al.

The Effects of AHCC®, a Standardized Extract of Cultured Lentinura edodes Mycelia, on Natural Killer and T Cells in Health and Disease: Reviews on Human and Animal Studies

J Immunol Res. 2019; 2019: 3758576

西岡浩ら

AHCCの自然免疫増強作用

メディカル・サイエンス・ダイジェスト. 2009; 35(6): 241-244.

Philippa J Cheetham, et al.

Diet and prostate cancer – a holistic approach to management

Arch Esp Urol. 2011; 64(8): 720-34.

Ghazaleh Jamalipour Soufi, et al.

SARS-CoV-2 (COVID-19): New Discoveries and Current Challenges

Appl Sci. 2020; 10(10): 3641.

Francesco Di Pierro, et al.

Possible therapeutic role of a highly standardized mixture of active compounds derived from cultured Lentinula edodes mycelia (AHCC) in patients infected with 2019 novel coronavirus

Minerva Gastroenterol Dietol. 2020; 66(2): 172-176.

三栖茉奈美ら

AHCC®の多様な機能性 ～症例報告～

New Food Industry. 2017; 59(2): 14-21.

堀内大ら

コンパニオンアニマルにおける補完代替医療とAHCC®，GCP®

CAP. 2012; 4: 53-57.

西澤孝志ら

βグルカンよりもαグルカン（担子菌由来AHCC 配合リキッド）がマクロファージを活性化させる　～担がん動物への展望～

CAP. 2011 Apr.

小沼守ら

当院の犬皮膚科におけるサプリメント療法

小動物臨床. 2008; 27(6): 340-346.

西澤幹雄ら

Assessment of anti-inflammatory effects of Japanese Kampo medicine versus functional foods

FFHD. 2019; 9(2): 79-91.

西岡浩ら

担子菌培養抽出物（AHCC®）の多様な機能性

メディカル・サイエンス・ダイジェスト. 2019; 45(2): 127-130.

若命浩二

菌類培養液の研究と機能性開発

アグリバイオ. 2017; 1(4): 438-442.

Robert M Hackman, et al.

Forecasting Nutrition Research in 2020

J Am Coll Nutr. 2014; 33(4): 340-6.

Catherine Ulbricht, et al.

An Evidence-Based Systematic Review of Active Hexose Correlated Compound (AHCC) by the Natural Standard Research Collaboration

J Diet Suppl. 2013; 10(3): 264-308.

Shinil K Shah, et al.

An Evidence-Based Review of a Lentinula edodes Mushroom Extract as Complementary Therapy in the Surgical Oncology Patient

J Parenter Enteral Nutr. 2011; 35(4): 449-58.

Barry W Ritz

Active Hexose Correlated Compound (AHCC) and Immune Outcomes in Humans: A Review

Natural Medicine Journal. 2011; 3(1): 3-7.

上山泰男

食品AHCCの機能性について―基礎と臨床―

南方資源利用技術研究会誌. 2011; 27(1): 1-8.

三浦健人ら

Basic and Clinical Studies on Active Hexose Correlated Compound

Biotechnology in Functional Foods and Nutraceuticals. 2010: 51-58.

三浦健人ら

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