Oligonol®Study Results

Scientific Publications

.List of Scientific Publications

To date, universities and research institutes around the world have been engaged in research on Oligonol, and more than 100 papers have been published.

Exercise and sport

Exercise performance

Masaaki Sugita, et al.

Oligomerized polyphenols in lychee fruit extract supplements may improve high-intensity exercise performance in male athletes: a pilot study

Physical Activity and Nutrition 2021;25(3):8-15.

Clinical
Exercise performance

Seung Wan Kang, et al.

Oligomerized lychee fruit extract (OLFE) and a mixture of vitamin C and vitamin E for endurance capacity in a double blind randomized controlled trial

J Clin Biochem Nutr. 2012 Mar; 50(2): 106-13.

Clinical
Mountain climbing, hypoxia

Junichi Nagasawa, et al.

Exercise and oxidative stress in hypoxia

J Phys Fitness Sports Med. 2013; 2(4): 481-486.

Clinical
Mountain climbing, hypoxia

Junichi Nagasawa, et al.

Oxidative Stress in Hypobaric and Normobaric Hypoxia and Antioxidant Effect of Oligonol

Japanese Journal of Mountain Medicine. 2010; 30: 118-124.

Clinical
Physical fatigue

Tetsuya Okuyama, et al.

The Ameliorative Effect of the Oligomerized-polyphenol from Litchi chinensis Fruit Extract (OPLFE) on Temporary Physical Fatigue for University Track and Field Athletes -The Second Report Focused on the Subjective Assessments-

Japanese Pharmacology & Therapeutics. 2018; 46(8): 1425-1431.

Clinical
Physical fatigue

Hideki Ohno, et al.

The Supplementation of Oligonol, the New Lychee Fruit-derived Polyphenol Converting into a Low-molecular Form, Has a Positive Effect on Fatigue during Regular Track-and-field Training in Young Athletes

Adv Exer Sport Physiol. 2008; 13(4): 93-99.

Clinical

Mikio Nishizawa, et al.

Supplementation with a Flavanol-rich Lychee Fruit Extract Influences the Inflammatory Status of Young Athletes

Phytother Res. 2011 Oct; 25(10): 1486-93.

Clinical

Jeong-Beom Lee, et al.

The effect of Oligonol intake on cortisol and related cytokines in healthy young men

Nutr Res Pract. 2010 Jun; 4(3): 203-7.

Clinical

Miku Tsukamoto-Kusakabe, et al.

Effect of polyphenol converting into a low-molecular form on oxidative stress and serum total antioxidative capacity in high-intensity intermittent spring exercise

Japan Journal of Physical Education, Health and Sport Sciences. 2010; 45: 1-9.

Clinical

Hideki Ohno, et al.

Antioxidant Supplementation in High Altitude Mountaineering: Focusing on Oligonol

Japanese Journal of Mountain Medicine. 2007; 27: 43-60.

Clinical

Blood flow

Blood flow

Kentaro Kitadate, et al.

Effect of Lychee Fruit Extract (Oligonol) on Peripheral Circulation, a Pilot Study

Natural Medicine Journal. 2014; 6(7).

Clinical
Heat stroke

JeongBeom Lee, et al.

Oligonol Supplementation Modulates Plasma Volume and Osmolality and Sweating After Heat Load in Humans

J Med Food. 2015 May; 18(5): 578-83.

Clinical
Heat stroke

Jeong Beom Lee, et al.

Beneficial effect of Oligonol supplementation on sweating response under heat stress in humans

Food Funct. 2014 Oct; 5(10): 2516-20.

Clinical
Heat stroke

Young Oh Shin, et al.

Oligonol Supplementation Attenuates Body Temperature and the Circulating Levels of Prostaglandin E2 and Cyclooxygenase-2 After Heat Stress in Humans

J Med Food. 2013 Apr; 16(4): 318-23.

Clinical
Heat stroke

Young-Oh Shin, et al.

Effect of Oligonol Intake on Cortisol and Cytokines, and Body Temperature after Leg Immersion into Hot Water

Food Sci Biotechnol. 2011; 20(3): 659-663.

Clinical
Heat stroke, immunity

Young Oh Shin, et al.

The Effect of Oligonol Intake on Leukocytes, Serum HSP70, and Body Temperature after heat stress

J.KSLES. 2012; 19(1), 137-145.

Basic
Tinnitus

Takahiro Maeda, et al.

Investigation of the Amelioration Effects of Oligonol® on Tinnitus in Randomized Double-blinded Placebo-controlled Trial

Japanese Pharmacology & Therapeutics. 2016; 44(9): 1329-1336.

Clinical

Metabolic syndrome and aging

Diabetes

Chan Hum Park, et al.

Oligonol, a low-molecular-weight polyphenol derived from lychee peel, attenuates diabetes-induced pancreatic damage by inhibiting inflammatory responses via oxidative stress-dependent mitogen-activated protein kinase/nuclear factor-kappa B signaling

Phytother Res. 2018 Dec; 32(12): 2541-2550.

Basic
Diabetes

Himanshu Kumar Bhakta, et al.

Oligonol promotes glucose uptake by modulating the insulin signaling pathway in insulin-resistant HepG2 cells via inhibiting protein tyrosine phosphatase 1B

Arch Pharm Res. 2017 Nov; 40(11): 1314-1327.

Basic
Diabetes, Alzheimer’s disease

Jae Sue Choi, et al.

Inhibitory evaluation of oligonol on α-glucosidase, protein tyrosine phosphatase 1B, cholinesterase, and β-secretase 1 related to diabetes and Alzheimer’s disease

Arch Pharm Res. 2016; 39(3): 409-420.

Basic
Diabetes, hepatic protection

Jeong Sook Noh, et al.

Treatment with Oligonol, a low-molecular Polyphenol derived from lychee fruit, attenuates diabetes-induced hepatic damage through regulation of oxidative stress and lipid metabolism

Br J Nutr. 2011 Oct; 106(7): 1013-22.

Basic
Diabetes, hyperlipidemia

Jun Takanari, et al.

Oligonol, a low molecular weight polyphenol of lychee fruit extract, suppresses absorption of glucose and fat

Clin Pharmacol Ther. 2017; 27(4): 195-205.

Basic
Diabetes, hyperlipidemia, sarcopenia

Hung-Wen Liu, et al.

Flavanol-rich lychee fruit extract alleviates diet-induced insulin resistance via suppressing mTOR/SREBP-1 mediated lipogenesis in liver and restoring insulin signaling in skeletal muscle

Mol Nutr Food Res. 2016 Oct; 60(10): 2288-2296.

Basic
Diabetes, pancreatic protection

Chan Hum Park, et al.

Oligonol, a low-molecular-weight polyphenol derived from lychee fruit, protects the pancreas from apoptosis and proliferation via oxidative stress in streptozotocin-induced diabetic rats

Food Funct. 2016 Jul 13; 7(7): 3056-3063.

Basic
Diabetes, renal protection

Hung-Wen Liu, et al.

Low-molecular-weight polyphenols protect kidney damage through suppressing NF-κB and modulating mitochondrial biogenesis in diabetic db/db mice

Food Funct. 2016 Apr; 7(4): 1941-9.

Basic
Diabetes, renal protection

Chan Hum Park, et al.

Oligonol, a low-molecular-weight polyphenol derived from lychee fruit, attenuates gluco-lipotoxicity mediated renal disorder in type 2 diabetic db/db mice

Drug Discov Ther. 2015 Feb; 9(1): 13-22.

Basic
Diabetes, renal protection

Chan Hum Park, et al.

Oligonol, a Low-Molecular-Weight Polyphenol Derived from Lychee Fruit, Attenuates Diabetes-Induced Renal Damage through the Advanced Glycation End Product–Related Pathway in db/db Mice

J Nutr. 2014 Aug; 144(8): 1150-7.

Basic
Diabetes, renal protection

Jeong Sook Noh, et al.

Hypolipidaemic and antioxidative effects of oligonol, a low-molecular-weight polyphenol derived from lychee fruit, on renal damage in type 2 diabetic mice.

Br J Nutr. 2010 Oct; 104(8): 1120-8.

Basic
Diabetes, vascular endothelial function

Xiao-Hong Zhang, et al.

Beneficial effect of the oligomerized polyphenol oligonol on high glucose-induced changes in eNOS phosphorylation and dephosphorylation in endothelial cells

Br J Pharmacol. 2010 Feb; 159(4): 928-38.

Basic
Gout

Yuji Moriwaki, et al.

Effects of Oligonol®, an oligomerized polyphenol formulated from lychee fruit, on serum concentration and urinary excretion of uric acid

J Funct Foods. 2011; 3(1): 13-16.

Clinical
Hair loss

Koji Wakame, et al.

Comparison of Effects on Gene Expression Activity of Low-Molecular-Weight Lychee Fruit Polyphenol (Oligonol®), Adenosine, and Minoxidil in Human Dermal Papilla Cells

J Biomed Transl Res. 2017; 1, 6-12.

Basic
Hyperlipidemia

Khota Hayashi, et al.

Oligonol, a Low-molecular Weight Polyphenol Extracted from Lychee Fruit, Modulates Cholesterol Metabolism in Rats within a Short Period

J Oleo Sci. 2020 Sep 2; 69(9): 1077-1085.

Basic
Hyperlipidemia

Jae-Yeo Park, et al.

Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model

BMC Complement Altern Med. 2015 Jun 16; 15: 185.

Basic
Hyperlipidemia

Junetsu Ogasawara, et al.

Oligonol-induced Degradation of Perilipin 1 is Regulated through Lysosomal Degradation Machinery

Nat Prod Commun. 2012 Sep; 7(9): 1193-6.

Basic
Hyperlipidemia

Junetsu Ogasawara, et al.

Comparison of the Effect of Oligonol, A New Lychee Fruit-derived Low Molecular Form of Polyphenol, and Epigallocatechin-3-gallate on Lipolysis in Rat Primary Adipocytes

Phytother Res. 2011 Mar; 25(3): 467-71.

Basic
Hyperlipidemia

Junetsu Ogasawara, et al.

Oligonol, an oligomerized lychee fruit-derived polyphenol, activates the Ras/ Raf-1/ MEK1/2 cascade independent of the IL-6 signaling pathway in rat primary adipocytes

Biochem Biophys Res Commun. 2010 Nov 19; 402(3): 554-9.

Basic
Hyperlipidemia, thrombus

Ryu Miyagawa, et al.

The effect of insulin on the production of plasminogen activator inhibitor type-1 in HepG2 cells

Heart. 2010; 42(9): 1153-1158.

Basic
Metabolic syndrome

Suhad M Bahijri, et al.

Oligonol Supplementation Decreases Cardiometabolic Risk Factors, and the Prevalence of Metabolic Syndrome in a Sample of Overweight and Obese Saudi Females

Annu Res Rev Biol. 2017; 16(2).

Clinical
Metabolic syndrome

Hironobu Uchiyama, et al.

Global Liver Gene Expression Analysis on a Murine Metabolic Syndrome Model Treated by Low-molecular-weight Lychee Fruit Polyphenol (Oligonol®)

Anticancer Res. 2016 Jul; 36(7): 3705-13.

Basic
Obesity

Zaure Zhaparkhanova, et al.

Use of Oligonol® in Overweight and Obesity

Endocrinology Quick Report. 2018; 2(50): 31-34.

Basic
Obesity

Masaki Taga, et al.

Anti-obesity effects of Oligonol in healthy subjects: a double blind, randomized placebo-controlled trial

Clinical Pharmacology and Therapy. 2016; 26(3): 85-96.

Clinical
Obesity

Jun Nishihira, et al.

Amelioration of abdominal obesity by low-molecular-weight polyphenol (Oligonol) from lychee

J Funct Foods. 2009; 1(4): 341-348.

Clinical
Obesity, Hyperlipidemia

Suhad M Bahijri, et al.

Supplementation with Oligonol, Prevents Weight Gain and Improves Lipid Profile in Overweight and Obese Saudi Females

Curr Nutr Food Sci. 2018 Apr; 14(2): 164-170.

Clinical
Obesity, hyperlipidemia

Jae-Yeo Park, et al.

Inhibition of Adipogenesis by Oligonol through Akt-mTOR Inhibition in 3T3-L1 Adipocytes

Evid Based Complement Alternat Med. 2014; 2014: 895272.

Basic
Obesity, hyperlipidemia

Swati Kalgaonkar, et al.

Bioactivity of a flavanol-rich lychee fruit extract in adipocytes and its effects on oxidant defense and induces of metabolic syndrome in animal models

Phytother Res. 2010 Aug; 24(8): 1223-8.

Basic
Obesity, hyperlipidemia

Junetsu Ogasawara, et al.

Oligonol, a new lychee fruit-derived low-molecular form of polyphenol, enhances lipolysis in primary rat adipocytes through activation of the ERK1/2 pathway

Phytother Res. 2009 Nov; 23(11): 1626-33.

Basic
Obesity, hyperlipidemia

Takuya Sakurai, et al.

Antioxidative effects of a new lychee fruit derived polyphenol mixture, Oligonol, converted into a low-molecular form in adipocytes

Biosci Biotechnol Biochem. 2008 Feb; 72(2): 463-76.

Basic
Obesity, hyperlipidemia, diabetes

Koji Wakame

Functions of low molecular weight polyphenols from lychee fruit

FOOD STYLE 21. 2007; 125: 65.

Review
Sirtuin autophagy

Seul-Ki Park, et al.

Oligonol promotes anti-aging pathways via modulation of SIRT1-AMPK-Autophagy Pathway

Nutr Res Pract. 2016 Feb; 10(1): 3-10.

Basic

Beauty

Skin protection

Joydeb Kumar Kundu, et al.

Oligonol, a lychee fruit-derived low molecular weight polyphenol formulation, inhibits UVB-induced cyclooxygenase-2 expression, and induces NAD(P)H:quinone oxidoreductase-1 expression in hairless mouse skin

J Funct Foods. 2009; 1(1): 98-108.

Basic

Koji Wakame, et al.

Antibacterial and beautiful skin effects of low molecular weight polyphenols

Fragrance journal. 2009; 37(11): 65-68.

Clinical

Review

Manufacturing

Takashi Tanaka, et al.

Production of oligomeric proanthocyanidins by fragmentation of polymers

Japanese Journal of Food Chemistry. 2007; 14(3): 134-139.

Basic
Obesity

Asuka Yasueda, et al.

Review: Evidence-based Clinical Research of Anti-obesity Supplements in Japan

Immunol Endocr Metab Agents Med Chem. 2013 Aug; 13(3): 185-195.

Review
Obesity, hyperlipidemia

Takuya Sakurai, et al.

Antioxidant effects of a novel low molecular weight polyphenol, Oligonol

FOOD FUNCTION. 2009; 5(1): 2-7.

Review
Pet animal

Mamoru Onuma, et al.

The supplementation therapy of caine dermatology in my hospital

Japanese Journal of Small Animal Practice. 2008; 27(6): 340-346.

Veterinary
Physical fatigue

Jun Takanari, et al.

Anti-fatigue effects of Oligonol, a low-molecular-weight polyphenol, a “next-generation sports nutrition

FOOD STYLE 21. 2014; 209: 71-74.

Review
Supercooling

Chikako Kuwabara, et al.

Analysis of supercooling activity of tannin-related polyphenols

Cryobiology. 2013 Aug; 67(1): 40-9.

Review

Robert Fried, et al.

Multiple Protective Functions of Oligonol from Lychee

Type 2 Diabetes: Cardiovascular and Related Complications and Evidence-based Complementary Treatments (CHES). 2020: 269-273.

Book

Yousef A Al-Dashti, et al.

Dietary Flavanols: A Review of Select Effects on Vascular Function, Blood Pressure, and Exercise Performance

J Am Coll Nutr. Sep-Oct 2018; 37(7): 553-567.

Review

Kazumi Hayama, et al.

Health-promoting effects of a oligomerized polyphenol, oligonol on the athleates and elderly people

Bulletin of Sports and Medical Science. 2014; 6: 17-21.

Review

Koji Wakame, et al.

Functions of a new generation of low molecular weight polyphenols (Oligonol)

aromatopia. 2011; 20(4): 87-91.

Review

Jun Takanari, et al.

Functions of a new generation of low molecular weight polyphenols (Oligonol)

New Food Industry. 2011; 53(3): 9-21.

Review

Takehito Miura, et al.

The Function of the Next Generation Polyphenol, “Oligonol”

Biotechnology in Functional Foods and Nutraceuticals. 2010: 91-101.

Book

Takehito Miura, et al.

Functions of Oligonol, a New Generation Polyphenol

Japan Food Science. 2010; 49(1): 37-44.

Review

Takehito Miura, et al.

The Function of the Next Generation of Polyphenol “Oligonol”

Japanese Journal of Complementary and Alternative Medicine. 2008; 5(3): 163-171.

Review

Other

Action mechanism

Ryota Yamanishi, et al.

The Anti-inflammatory Effects of Flavanol-rich Lychee Fruit Extract in Rat Hepatocytes

PLoS One. 2014 Apr 4; 9(4): e93818.

Basic
Air pollution

Takumi Shibukawa, et al.

Absorption of Nitrogen Dioxide by the Polyphenol Solution

Kagaku kogaku ronbunshu. 2011; 37(2): 162-166.

Basic
Alzheimer’s disease

Xiao Chen, et al.

Flavanol-rich lychee fruit extract substantially reduces progressive cognitive and molecular deficits in a triple-transgenic animal model of Alzheimer disease

Nutr Neurosci. 2019 Oct 11; 1-15.

Basic
Alzheimer’s disease

Yoon Young Choi, et al.

Oligonol improves memory and cognition under an amyloid β25-35-induced Alzheimer’s mouse model

Nutr Res. 2014 Jul; 34(7): 595-603.

Basic
Betanodavirus

Toru Ichinose, et al.

Evaluation of antiviral activity of Oligonol, an extract of Litchi chinensis, against betanodavirus

Drug Discov Ther. 2013 Dec; 7(6): 254-60.

Basic
Cognitive function

Takuya Sakurai, et al.

Oligomerized lychee fruit-derived polyphenol attenuates cognitive impairment in senescence-accelerated mice and endoplasmic reticulum stress in neuronal cells

Br J Nutr. 2013 Nov 14; 110(9): 1549-58.

Basic
Colitis

K-J Kim, et al.

Oligonol prevented the relapse of dextran sulfate sodium-ulcerative colitis through enhancing NRF2-mediated antioxidative defense mechanism

J Physiol Pharmacol. 2018 Jun; 69(3).

Basic
Colitis

Hye-Won Yum, et al.

Oligonol Inhibits Dextran Sulfate Sodium-Induced Colitis and Colonic Adenoma Formation in Mice

Antioxid Redox Signal. 2013 Jul 10; 19(2): 102-14.

Basic
Diabetes, sarcopenia

Hung-Wen Liu, et al.

Oligonol, a Low-Molecular Weight Polyphenol Derived from Lychee, Alleviates Muscle Loss in Diabetes by Suppressing Atrogin-1 and MuRF1

Nutrients. 2017 Sep 20; 9(9): 1040.

Basic
Esophagitis, gastric ulcer

Seong-Soo Roh, et al.

Low-Molecular-Weight Oligonol, a Polyphenol Derived from Lychee Fruit, Attenuates Experimental Reflux Esophagitis and HCl/Ethanol-Induced Gastric Ulcer

J Med Food. 2017 Dec; 20(12): 1214-1221.

Basic
Hepatitis

Jeonghyeon Bak, et al.

Oligonol Ameliorates CCl4-Induced Liver Injury in Rats via the NK-Kappa B and MAPK Signaling Pathways

Oxid Med Cell Longev. 2016; 2016: 3935841.

Basic
Immunity

Jeong Beom Lee, et al.

Oligonol Supplementation Affects Leukocyte and Immune Cell Counts after Heat Loading in Humans

Nutrients. 2014 Jun 24; 6(6): 2466-77.

Clinical
Influenza

Noboru Uchide, et al.

Antioxidant Therapy as a Potential Approach to Severe Influenza-Associated Complications

Molecules. 2011 Feb 28; 16(3): 2032-52.

Basic
Influenza

Leila Gangehei, et al.

Oligonol a low molecular weight polyphenol of lychee fruit extract inhibits proliferation of influenza virus by blocking reactive oxygen species-dependent ERK phosphorylation

Phytomedicine. 2010 Nov; 17(13): 1047-56.

Basic
Malignant melanoma, lung metastasis

Sung-Jae Lee, et al.

Inhibition of Lung Metastasis in Mice by Oligonol

Phytother Res. 2009 Jul; 23(7): 1043-6.

Basic
Neurodegenerative disease

Jae Hyun Ahn, et al.

Protective role of oligonol from oxidative stress-induced inflammation in C6 glial cell

Nutr Res Pract. 2015 Apr; 9(2): 123-8.

Basic
Opportunistic infection, Candida

Yoichi Nakagawa, et al.

Anti-Candida effectiveness of a candy containing citral, cinnamaldehyde, oligonol, and capric acid for oral candidiasis

Oral Therapeutics and Pharmacology. 2018; 37(3): 101-107.

Clinical
Opportunistic infection, Candida

Kazumi Hayama, et al.

Inhibitory effects of several saturated fatty acids and their related fatty alcohols on the growth of Candida albicans

Drug Discov Ther. 2015 Dec; 9(6): 386-90.

Basic
Opportunistic infection, Candida

Kazumi Hayama, et al.

Development of a new aroma candy for maintenance of the oral health

Med Mycol Res. 2015; 6(1): 3-9.

Clinical
Opportunistic infection, Candida

Motofumi Suzuki, et al.

The Effects of an Aroma Candy on Oral Candida albicans Colony-forming Units (CFU) and Oral Hygiene States in Healthy Elderly Carrying Candida albicans

Medical Mycology Journal. 2015; 56: J31-J40.

Clinical
Opportunistic infection, Candida

Kazumi Hayama, et al.

Anti-Candida Activity of Aroma Candy and Its Protective Activity Against Murine Oral Candidiasis

Medical Mycology Journal. 2015; 56: J23-J29.

Basic
Opportunistic infection, Candida

Kazumi Hayama, et al.

Therapeutic Effect of Oligonol, a Low-molecular Polyphenol Formulation Derived from Lychee Fruits on Murine Oral Candidiasis

Japanese Journal of Medical Mycology. 2010; 51(3): 137–142.

Basic
Ovarian cancer

Miseon Kim, et al.

Oligonol, a Low Molecular Weight Polyphenol, Enhances Apoptotic Cell Death in Ovarian Cancer Cells via Suppressing NF-κB Activation

Nutr Cancer. 2019; 71(1): 141-148.

Basic
Prostatitis

İlhan Öztekin, et al.

Therapeutic Effects of Oligonol, Acupuncture, and Quantum Light Therapy in Chronic Nonbacterial Prostatitis

Evid Based Complement Alternat Med. 2015; 2015: 687196.

Basic
Prostatitis

Hakan Akdere, et al.

Analgesic Effects of Oligonol, Acupuncture and Quantum Light Therapy on Chronic Nonbacterial Prostatitis

Iran Red Crescent Med J. 2015 Apr 25; 17(4): e26006.

Basic
Retinal protecion

Jun Kisugi, et al.

Suppression of N-Methyl-N-Nitrosourea-Induced Retinal Damage in Mice by Oligonol, an Oligomerized Polyphenol Formulation

ABC. 2014; 4(2), 138-147.

Basic
Sarcopenia

Yun-Ching Chang, et al.

Oligonol Alleviates Sarcopenia by Regulation of Signaling Pathways Involved in Protein Turnover and Mitochondrial Quality

Mol Nutr Food Res. 2019 May; 63(10): e1801102.

Basic
Sexual performance

Koji Wakame, et al.

Attempt to develop a sexual function-improving drink containing various natural food ingredients

FOOD STYLE 21. 2011; 165: 41-43.

Clinical
Supercooling

Seizo Fujikawa, et al.

Supercooling-Promoting (Anti-ice Nucleation) Substances

Survival Strategies in Extreme Cold and Desiccation. 2018: 289-320.

Book
Supercooling

Seizo Fujikawa, et al.

Current Research on Supercooling Accelerators

Functions and Applications of Antifreeze Protein. 2018: 180-190.

Book
Supercooling

Toshie Koyama, et al.

Anti-ice nucleating activity of polyphenol compounds against silver iodide

Cryobiology. 2014 Oct; 69(2): 223-8.

Basic

Naeun Lee, et al.

Oligonol, a lychee fruit-derived low-molecular form of polyphenol mixture, suppresses inflammatory cytokine production from human monocytes

Hum Immunol. 2016 Jun; 77(6): 512-5.

Basic

Kentaro Kitadate, et al.

Thirteen-week oral dose toxicity study of Oligonol containing oligomerized polyphenols extracted from lychee and green tea

Regul Toxicol Pharmacol. 2014 Feb; 68(1): 140-6.

Basic

Katsuhiko Suzuki, et al.

Functional Analyses of Oligonol by Novel Neutrophil Activity Measurement System

Japanese Journal of Complementary and Alternative Medicine. 2013; 10(1): 59-62.

Basic

Mahesh Thirunavukkarasu, et al.

Safety of oligonol, a highly bioavailable lychee-derived polyphenolic antioxidant, on liver, kidney and heart function in rats

Toxicol Mech Methods. 2012 Sep; 22(7): 555-9.

Basic

Hajime Fujii, et al.

Acute, subchronic and genotoxicity studies conducted with Oligonol, an oligomerized polyphenol formulated from lychee and green tea extracts

Food Chem Toxicol. 2008 Dec; 46(12): 3553-62.

Basic