論文

西澤幹雄ら

Anti-inflammatory Effects of Enzyme-treated Asparagus Extract and Its Constituents in Hepatocytes

FFHD. 2016; 6(2): 91-109.

伊藤知洋ら

Enzyme-Treated Asparagus Extract Promotes Expression of Heat Shock Protein and Exerts Antistress Effects

J Food Sci. 2014; 79(3): H413-9.

高成準ら

Effect of Enzyme-Treated Asparagus Extract (ETAS) on Psychological Stress in Healthy Individuals

J Nutr Sci Vitaminol. 2016; 62(3): 198-205.

伊藤知洋ら

Effects of Enzyme-Treated Asparagus Extract on Heat Shock Protein 70, Stress Indices, and Sleep in Healthy Adult Men

J Nutr Sci Vitaminol. 2014; 60(4): 283-90.

伊藤知洋ら

Enzyme-Treated Asparagus Extract Promotes Expression of Heat Shock Protein and Exerts Antistress Effects

J Food Sci. 2014; 79(3): H413-9.

酒井咲紀ら

Improved Sleep Quality and Work Performance Among Shift Workers Consuming a “Foods with Function Claims” Containing Asparagus Extract

J UOEH. 2021; 43(1): 15-23.

出口直幸ら

タクシー運転手の睡眠状態や疲労にアスパラガス抽出物含有加工食品摂取が及ぼす影響の検討　─非盲検・無作為化並行群間比較試験─

日本交通科学学会誌. 2019; 19(1): 33-44.

加藤真奈美ら

夜型生活者におけるアスパラガス抽出物含有加工食品（ONR-8）の睡眠状況に及ぼす影響の探索的検討　―無作為化二重盲検プラセボ対照クロスオーバー比較試験―

薬理と治療. 2016; 44(6): 887-893.

加藤真奈美ら

平日と休日で睡眠覚醒リズムが異なる人におけるアスパラガス抽出物含有加工食品（ONR—8）の休日明けの寝覚め感ならびに睡眠の質に対する効果　―無作為化二重盲検プラセボ対照クロスオーバー比較試験―

薬理と治療. 2016; 44(5): 743-750.

伊藤知洋ら

Effects of Enzyme-Treated Asparagus Extract on Heat Shock Protein 70, Stress Indices, and Sleep in Healthy Adult Men

J Nutr Sci Vitaminol. 2014; 60(4): 283-90.

Natalia Mikhailichenko, et al.

Evaluation of the beneficial effects of ETAS® on normal aging or mild cognitive impairment subjects: A pilot randomized controlled trial

Journal of Pharmacy & Pharmacognosy Research, 12 (1), 154-165, 2024

銭本隆行ら

Effect of a Standardized Extract of Asparagus officinalis Stem (ETAS®50) on Cognitive Function, Psychological Symptoms, and Behavior in Patients with Dementia: A Randomized Crossover Trial

Evid Based Complement Alternat Med. 2023; 2023: 9960094.

小笠原準悦ら

ETAS, an Enzyme-treated Asparagus Extract, Attenuates Amyloid β-Induced Cellular Disorder in PC12 Cells

Nat Prod Commun. 2014; 9(4): 561-4.

Yin-Ching Chan, et al.

A Standardized Extract of Asparagus officinalis Stem (ETAS®) Ameliorates Cognitive Impairment, Inhibits Amyloid Deposition via BACE-1 and Normalizes Circadian Rhythm Signaling via MT1 and MT2

Nutrients. 2019; 11(7): 1631.

Zhanglong Peng, et al.

Neuroprotective Effects of Asparagus officinalis Stem Extract in Transgenic Mice Overexpressing Amyloid Precursor Protein

J Immunol Res. 2021; 2021: 8121407.

小宇田智子ら

Enzyme-treated Asparagus Extract (ETAS) Enhances Memory in Normal Rats and Induces Neurite-outgrowth in PC12 Cells

Nat Prod Commun. 2017; 12(10): 1631-1633.

櫻井拓也ら

Enzyme-treated Asparagus officinalis Extract Shows Neuroprotective Effects and Attenuates Cognitive Impairment in Senescenceaccelerated Mice

Nat Prod Commun. 2014; 9(1): 101-6.

西岡浩

道産アスパラガスからの機能性食品ETASの開発と販売網の構築

グリーンテクノ情報. 2019; 14(4), 50-53.

菅谷健作ら

アスパラガス由来プロリン-3-アルキルジケトピペラジン（アスパラプロリン）

抗疲労・抗ストレス・睡眠改善食品の開発. 2020; 209-217.

前田哲宏

抗ストレス作用を有する新規機能性食品素材「酵素アスパラガス抽出物ETAS®」

グリーンテクノ情報. 2016; 12(2), 22-27.

高成準

ムードフード“酵素処理アスパラ抽出物”の新たな機能性

FOOD STYLE 21. 2016; 20(6): 55-58.

前田哲宏ら

新規抗ストレス機能性食品素材「酵素処理アスパラガス熱水抽出物“ETAS”」のご紹介

New Food Industry. 2015; 57(1): 27-34.

高成準ら

抗ストレス食品素材「酵素処理アスパラガス抽出物」の開発

FOOD STYLE 21. 2013; 17(8): 64-66.

伊藤知洋ら

酵素処理アスパラガス茎熱水抽出物の熱ショックタンパク質発現増強効果

New Food Industry. 2012; 54(8): 1-9.

Khoi Thieu Ho, et al.

Synergistic effect of standardized extract of Asparagus officinalis stem and heat shock on progesterone synthesis with lipid droplets and mitochondrial function in bovine granulosa cells

J Steroid Biochem Mol Biol. 2023; 225: 106181.

Khoi Thieu Ho, et al.

A standardized extract of Asparagus officinalis stem improves HSP70-mediated redox balance and cell functions in bovine cumulus-granulosa cells

Sci Rep. 2021; 11(1): 18175.

白土健ら

Standardized Extract of Asparagus officinalis Stem Attenuates SARS-CoV-2 Spike Protein-Induced IL-6 and IL-1β Production by Suppressing p44/42 MAPK and Akt Phosphorylation in Murine Primary Macrophages

Molecules. 2021; 26(20): 6189.

井上正一郎ら

Isolation and Structure Determination of a Heat Shock Protein Inducer, Asparagus-derived Proline-containing 3-Alkyldiketopiperazines (Asparaprolines), from a standardized extract of Asparagus officinalis stem

Nat Prod Commun. 2020; 15(3): 1-7.

伊藤知洋ら

Isolation, structural elucidation, and biological evaluation of a 5-hydroxymethyl-2-furfural derivative, asfural, from enzyme-treated asparagus extract

J Agric Food Chem. 2013; 61(38): 9155-9.

小宇田智子ら

Effects of a Standardized Extract of Asparagus officinalis Stem on Photoaging in the Epidermal Layer of the Skin Using Cultured Keratinocytes

Nat Prod Commun. 2019; 14(6): 1934578X1985734.

白土健ら

ETAS®50 Attenuates Ultraviolet-B-Induced Interleukin-6 Expression by Suppressing Akt Phosphorylation in Normal Human Dermal Fibroblasts

Evid Based Complement Alternat Med. 2018; 2018: 1547120.

白土健ら

Anti-Inflammatory Effect of ETAS®50 by Inhibiting Nuclear Factor-κB p65 Nuclear Import in Ultraviolet-B-Irradiated Normal Human Dermal Fibroblasts

Evid Based Complement Alternat Med. 2018; 2018: 5072986.

白土健ら

A standardized extract of Asparagus officinalis stem prevents reduction in heat shock protein 70 expression in ultraviolet-B-irradiated normal human dermal fibroblasts: an in vitro study

Environ Health Prev Med. 2018; 23(1): 40.

白土健ら

Enzyme-Treated Asparagus Extract Prevents’Hydrogen Peroxide-Induced Pro-Inflammatory Responses by Suppressing p65 Nuclear Translocation in Skin L929 Fibroblasts

Nat Prod Commun. 2016; 11(12): 1883-1888.

白土健ら

Enzyme-Treated Asparagus Extract Attenuates Hydrogen Peroxide-Induced Matrix Metalloproteinase-9 Expression in Murine Skin Fibroblast L929 Cells

Nat Prod Commun. 2016; 11(5): 677-80.

Francesca Paganelli, et al.

The Combination of AHCC and ETAS Decreases Migration of Colorectal Cancer Cells, and Reduces the Expression of LGR5 and Notch1 Genes in Cancer Stem Cells: A Novel Potential Approach for Integrative Medicine

Pharmaceuticals. 2021; 14(12): 1325.

藏満保宏ら

Enzyme-treated Asparagus Extract Down-regulates Heat Shock Protein 27 of Pancreatic Cancer Cells

In Vivo. 2018; 32(4): 759-763.

安枝明日香ら

Safety Evaluation of a Standardised Extract of Asparagus officinalis Stem in Healthy Volunteers: a Double-Blind and Randomised Controlled Trial

Journal of Herbal Medicine. 2023; 42:100789

伊藤知洋ら

Toxicological assessment of enzyme-treated asparagus extract in rat acute and subchronic oral toxicity studies and genotoxicity tests

Regul Toxicol Pharmacol. 2014; 68(2): 240-9.